Dealing with uncertainty is a part of human life, and no where does that become more apparent then when living with terminal cancer. Each treatment decision takes on an exaggerated importance, and we rely upon our oncologist to provide us with information to chose the best option in light of a heck of a lot of unknowns.
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Dealing with metastatic cancer is a bit like a cross between playing the Hunger Games with a Sisyphean game of blindfolded Whack-a-Mole thrown in just for fun. Almost no one wins; the only question is whether you can actually hit any or continue to hit all of the targets while blindfolded.